| 分子式 | C29H38N4O7 | 分子量 | 554.63462 |
| 退税率 | 海关编码 | ||
| 是否需要商检 | HS查询 | 是否危险品 | CHEMBLINK | SIGMA |
| 别名（英文） | 别名（中文） | ||
| 外观物理性质 | 储存条件 | ||
| 用途 | |||
| 备注信息 |
SMILES COC1=CC2=C(C=C1)N=C3C(=N2)O[C@H]4CN(C(=O)[C@@H](NC(=O)O[C@H]5[C@H](CCCCC3)C5)C(C)(C)C)[C@H](C(O)=O)C4 物理化学性质 Storage: -20℃ 2 yearsPurity: >99% 产品用途 MK-5172 is a novel NS3/4, a protease inhibitor for chronic HCV infection (Enzyme Ki for genotype1b, 2a, 2b and 3a at ＜0.02, 0.15, 0.02 and 0.7 nM, respectively). This agent has an attractive preclinical profile including high potency in vitro, significant liver exposure upon oral dosing, and potent inhibitory activity against viral variants that are resistant to other protease inhibitors in development. MK-5172 has also demonstrated anti-viral efficacy in a chimpanzee model of chronic HCV infection. 应用领域 上下游产品信息 化学品安全说明书(MSDS) 储运特性 |
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